human HPGD Over-expression AAV

Name 
AAV-h-HPGD
Cat No 
AAV-230151
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human HPGD.

AAV-230151
AAV-h-HPGD

Ready-to-use AAV expressing Human HPGD (hydroxyprostaglandin dehydrogenase 15-(NAD)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
15-PGDH; PGDH; PGDH1; PHOAR1; SDR36C1
Description (Vector)
HPGD encodes a member of the short-chain nonmetalloenzyme alcohol dehydrogenase protein family. The encoded enzyme is responsible for the metabolism of prostaglandins, which function in a variety of physiologic and cellular processes such as inflammation. Mutations in this gene result in primary autosomal recessive hypertrophic osteoarthropathy and cranioosteoarthropathy. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
3248
Gene Name (Vector)
hydroxyprostaglandin dehydrogenase 15-(NAD)
Gene Symbol
HPGD
HGNC ID
HGNC:5154
ORF Size (aa)
801
ORF Size (bp)
801 bp
RefSeq ID
NM_000860
RefSeq Synonyms
NM_001256307, NM_001256306, NM_001256305, NM_001256301, NM_001145816, NM_000860, BC018986,
Species
human
UniGene ID
Hs.596913

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.