human ZIC4 Over-expression AAV

Name
AAV-h-ZIC4

Cat No
AAV-228257

Availability
4-5 weeks

This is an AAV expressing Human ZIC4.

AAV-228257

AAV-h-ZIC4

Ready-to-use AAV expressing Human ZIC4 (Zic family member 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Description (Vector)

ZIC4 encodes a member of the ZIC family of C2H2-type zinc finger proteins. Members of this family are important during development, and have been associated with X-linked visceral heterotaxy and holoprosencephaly type 5. ZIC4 is closely linked to the gene encoding zinc finger protein of the cerebellum 1, a related family member on chromosome 3. Heterozygous deletion of these linked genes is involved in Dandy-Walker malformation, which is a congenital cerebellar malformation. Multiple transcript variants have been identified for this gene.

Gene ID

84107

Gene Name (Vector)

Zic family member 4

Gene Symbol

ZIC4

HGNC ID

HGNC:20393

ORF Size (aa)

1005

RefSeq ID

NM_032153

RefSeq Synonyms

NM_032153, NM_001243256, NM_001168379, NM_001168378, BC136339, BC126267,

Species

human

UniGene ID

Hs.415766

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.