human ZCRB1 Over-expression AAV

Name 
AAV-h-ZCRB1
Cat No 
AAV-228135
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human ZCRB1.

AAV-228135
AAV-h-ZCRB1

Ready-to-use AAV expressing Human ZCRB1 (zinc finger CCHC-type and RNA binding motif containing 1). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
MADP1; MADP-1; RBM36; SNRNP31; U11/U12 small nuclear ribonucleoprotein 31 kDa protein; U11/U12 snRNP 31 kDa protein; U11/U12 snRNP 31K; U11/U12-31K; ZCCHC19; zinc finger CCHC-type and RNA binding motif 1; zinc finger CCHC-type and RNA-binding motif-containing protein 1
Description (eCommerce)
Zinc finger CCHC-type and RNA-binding motif-containing protein 1 (ZCRB1) is a component of the U11/U12 snRNPs that are part of the U12-type spliceosome  [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8TBF4].
Description (Vector)
Pre-mRNA splicing is catalyzed by the spliceosome. U12-type spliceosome binds U12-type pre-mRNAs and recognizes the 5' splice site and branch-point sequence. U11 and U12 snRNPs are components of U12-type spliceosome and function as a molecular bridge connecting both ends of the intron. The protein encoded by this gene contains a RNA recognition motif. It was identified as one of the protein components of U11/U12 snRNPs. This protein and many other U11/U12 snRNP proteins are highly conserved in organisms known to contain U12-type introns. These proteins have been shown to be essential for cell viability, suggesting the key roles in U12-type splicing.
Gene ID
85437
Gene Name (eCommerce)
zinc finger CCHC-type and RNA binding motif containing 1
Gene Name (Vector)
zinc finger CCHC-type and RNA binding motif containing 1
Gene Symbol
ZCRB1
HGNC ID
HGNC:29620
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
654
Protein Name (eCommerce)
Zinc finger CCHC-type and RNA-binding motif-containing protein 1
RefSeq ID
NM_033114
RefSeq Synonyms
NM_033114, BC022543,
Research Areas
Gene Expression,mRNA Processing,mRNA Splicing,RNA Binding,RNA Processing,Zinc-finger
Research Areas (Faceted)
genetics,transcription_translation,cell_biology
Species
human
Target Sentence
Zinc finger CCHC-type and RNA-binding motif-containing protein 1 (ZCRB1) is a component of the U11/U12 snRNPs that are part of the U12-type spliceosome  [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q8TBF4].
UniGene ID
Hs.496279
UniProt ID (eCommerce)
Q8TBF4

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.