human VSIG4 Over-expression AAV

Name 
AAV-h-VSIG4
Cat No 
AAV-227562
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human VSIG4.

AAV-227562
AAV-h-VSIG4

Ready-to-use AAV expressing Human VSIG4 (V-set and immunoglobulin domain containing 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CRIg; Z39IG
Description (Vector)
VSIG4 encodes a v-set and immunoglobulin-domain containing protein that is structurally related to the B7 family of immune regulatory proteins. The encoded protein may be a negative regulator of T-cell responses. This protein is also a receptor for the complement component 3 fragments C3b and iC3b. Alternate splicing results in multiple transcript variants.
Gene ID
11326
Gene Name (Vector)
V-set and immunoglobulin domain containing 4
Gene Symbol
VSIG4
HGNC ID
HGNC:17032
ORF Size (aa)
1200
RefSeq ID
NM_007268
RefSeq Synonyms
NM_007268, NM_001257403, NM_001184831, NM_001184830, NM_001100431, BC010525,
Species
human
UniGene ID
Hs.8904

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.