human VDAC1 Over-expression AAV

Name 
AAV-h-VDAC1
Cat No 
AAV-227449
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human VDAC1.

AAV-227449
AAV-h-VDAC1

Ready-to-use AAV expressing Human VDAC1 (voltage dependent anion channel 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
PORIN; VDAC-1
Description (Vector)
VDAC1 encodes a voltage-dependent anion channel protein that is a major component of the outer mitochondrial membrane. The encoded protein facilitates the exchange of metabolites and ions across the outer mitochondrial membrane and may regulate mitochondrial functions. This protein also forms channels in the plasma membrane and may be involved in transmembrane electron transport. Alternate splicing results in multiple transcript variants. Multiple pseudogenes of this gene are found on chromosomes 1, 2 3, 6, 9, 12, X and Y.
Gene ID
7416
Gene Name (Vector)
voltage dependent anion channel 1
Gene Symbol
VDAC1
HGNC ID
HGNC:12669
ORF Size (aa)
852
RefSeq ID
NM_003374
RefSeq Synonyms
NM_003374, BC090042, BC071168, BC008482,
Species
human
UniGene ID
Hs.519320

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.