human VBP1 Over-expression AAV

Name 
AAV-h-VBP1
Cat No 
AAV-227421
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human VBP1.

AAV-227421
AAV-h-VBP1

Ready-to-use AAV expressing Human VBP1 (VHL binding protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
HIBBJ46; PFD3; PFDN3; prefoldin subunit 3; VBP-1; VHL-binding protein 1; von Hippel-Lindau binding protein 1; von Hippel-Lindau-binding protein 1
Description (eCommerce)
Von Hippel-Lindau-binding protein 1 (VBP1) binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. VPB1 binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P61758].
Description (Vector)
VBP1 interacts with the Von Hippel-Lindau protein to form an intracellular complex. Because it functions as a chaperone protein, it is suspected that it may play a role in the transport of the Von Hippel-Lindau protein from the perinuclear granules to the nucleus or cytoplasm.
Gene ID
7411
Gene Name (eCommerce)
VHL binding protein 1
Gene Name (Vector)
VHL binding protein 1
Gene Symbol
VBP1
HGNC ID
HGNC:12662
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
594
Protein Name (eCommerce)
Prefoldin subunit 3
RefSeq ID
NM_003372
RefSeq Synonyms
NM_003372, NM_001303545, NM_001303544, NM_001303543, BC046094,
Research Areas
Metabolism/Metabolic Process,Protein Folding,Translational Control
Research Areas (Faceted)
cell_biology,metabolism,transcription_translation
Species
human
Target Sentence
Von Hippel-Lindau-binding protein 1 (VBP1) binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. VPB1 binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P61758].
UniGene ID
Hs.436803
UniProt ID (eCommerce)
P61758

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.