human VAMP2 Over-expression AAV

Name 
AAV-h-VAMP2
Cat No 
AAV-227379
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human VAMP2.

AAV-227379
AAV-h-VAMP2

Ready-to-use AAV expressing Human VAMP2 (vesicle associated membrane protein 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
SYB2; VAMP-2
Description (Vector)
VAMP2 is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is thought to participate in neurotransmitter release at a step between docking and fusion. The protein forms a stable complex with syntaxin, synaptosomal-associated protein, 25 kD, and synaptotagmin. It also forms a distinct complex with synaptophysin. It is a likely candidate gene for familial infantile myasthenia (FIMG) because of its map location and because it encodes a synaptic vesicle protein of the type that has been implicated in the pathogenesis of FIMG.
Gene ID
6844
Gene Name (Vector)
vesicle associated membrane protein 2
Gene Symbol
VAMP2
HGNC ID
HGNC:12643
ORF Size (aa)
351
RefSeq ID
NM_014232
RefSeq Synonyms
NM_014232, NM_001330125, BC033870, BC019608, BC002737,
Species
human
UniGene ID
Hs.25348

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.