human USO1 Over-expression AAV

Name 
AAV-h-USO1
Cat No 
AAV-227280
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human USO1.

AAV-227280
AAV-h-USO1

Ready-to-use AAV expressing Human USO1 (USO1 vesicle transport factor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
general vesicular transport factor p115; P115; Protein USO1 homolog; TAP; transcytosis associated protein; Transcytosis-associated protein; USO1 vesicle docking protein homolog; VDP; vesicle docking protein p115; Vesicle-docking protein
Description (eCommerce)
p115 is a general vesicular transport factor required for intercisternal transport in the Golgi stack; it is required for transcytotic fusion and/or subsequent binding of the vesicles to the target membrane. May well act as a vesicular anchor by interacting with the target membrane and holding the vesicular and target membranes in proximity (By similarity) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O60763].
Description (Vector)
USO1 is a peripheral membrane protein which recycles between the cytosol and the Golgi apparatus during interphase. It is regulated by phosphorylation: dephosphorylated protein associates with the Golgi membrane and dissociates from the membrane upon phosphorylation. Ras-associated protein 1 recruits this protein to coat protein complex II (COPII) vesicles during budding from the endoplasmic reticulum, where it interacts with a set of COPII vesicle-associated SNAREs to form a cis-SNARE complex that promotes targeting to the Golgi apparatus. Transport from the ER to the cis/medial Golgi compartments requires the action of this gene product, GM130 and giantin in a sequential manner.
Gene ID
8615
Gene Name (eCommerce)
USO1 vesicle transport factor
Gene Name (Vector)
USO1 vesicle transport factor
Gene Symbol
USO1
HGNC ID
HGNC:30904
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2886
ORF Size (bp)
2886 bp
Protein Name (eCommerce)
General vesicular transport factor p115
RefSeq ID
NM_003715
RefSeq Synonyms
NM_003715, NM_001290049, BC032654,
Research Areas
Cell Cycle,Golgi Apparatus,Transport
Research Areas (Faceted)
cell_biology,cell_cycle,genetics
Species
human
Target Sentence
p115 is a general vesicular transport factor required for intercisternal transport in the Golgi stack; it is required for transcytotic fusion and/or subsequent binding of the vesicles to the target membrane. May well act as a vesicular anchor by interacting with the target membrane and holding the vesicular and target membranes in proximity (By similarity) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O60763].
UniGene ID
Hs.292689
UniProt ID (eCommerce)
O60763

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.