human UPB1 Over-expression AAV

Name 
AAV-h-UPB1
Cat No 
AAV-227221
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human UPB1.

AAV-227221
AAV-h-UPB1

Ready-to-use AAV expressing Human UPB1 (beta-ureidopropionase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BUP1
Description (Vector)
UPB1 encodes a protein that belongs to the CN hydrolase family. Beta-ureidopropionase catalyzes the last step in the pyrimidine degradation pathway. The pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidine dehydrogenase (DHPDH), dihydropyrimidinase (DHP) and beta-ureidopropionase (UP) to beta-alanine and beta-aminoisobutyric acid, respectively. UP deficiencies are associated with N-carbamyl-beta-amino aciduria and may lead to abnormalities in neurological activity.
Gene ID
51733
Gene Name (Vector)
beta-ureidopropionase 1
Gene Symbol
UPB1
HGNC ID
HGNC:16297
ORF Size (aa)
1155
RefSeq ID
NM_016327
RefSeq Synonyms
NM_016327, BC139840, BC131703,
Species
human
UniGene ID
Hs.474388

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.