human UGCG Over-expression AAV

Name 
AAV-h-UGCG
Cat No 
AAV-227133
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human UGCG.

AAV-227133
AAV-h-UGCG

Ready-to-use AAV expressing Human UGCG (UDP-glucose ceramide glucosyltransferase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
GCS; GLCT1
Description (Vector)
Glycosphingolipids (GSLs) are a group of membrane components that contain lipid and sugar moieties. They are present in essentially all animal cells and are believed to have important roles in various cellular processes. UDP-glucose ceramide glucosyltransferase catalyzes the first glycosylation step in glycosphingolipid biosynthesis. The product, glucosylceramide, is the core structure of more than 300 GSLs. UGCG is widely expressed and transcription is upregulated during keratinocyte differentiation.
Gene ID
7357
Gene Name (Vector)
UDP-glucose ceramide glucosyltransferase
Gene Symbol
UGCG
HGNC ID
HGNC:12524
ORF Size (aa)
1185
ORF Size (bp)
1185 bp
RefSeq ID
NM_003358
RefSeq Synonyms
NM_003358, BC038711,
Species
human
UniGene ID
Hs.593014

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.