human UBXN4 Over-expression AAV

Name 
AAV-h-UBXN4
Cat No 
AAV-227096
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human UBXN4.

AAV-227096
AAV-h-UBXN4

Ready-to-use AAV expressing Human UBXN4 (UBX domain protein 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
erasin; UBX domain containing 2; UBX domain-containing 1; UBX domain-containing protein 2; UBX domain-containing protein 4; UBXD2; UBXDC1
Description (eCommerce)
UBX domain-containing protein 4 (UBXN4) is Involved in endoplasmic reticulum-associated protein degradation (ERAD). It acts as a platform to recruit both UBQLN1 and VCP to the ER during ERAD (PubMed:19822669) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q92575].
Description (Vector)
UBXD2 is an integral membrane protein of the endoplasmic reticulum (ER) that binds valosin-containing protein (VCP; MIM 601023) and promotes ER-associated protein degradation (ERAD) (Liang et al., 2006 (PubMed 16968747)).(supplied by OMIM, Mar 2008)
Gene ID
23190
Gene Name (eCommerce)
UBX domain protein 4
Gene Name (Vector)
UBX domain protein 4
Gene Symbol
UBXN4
HGNC ID
HGNC:14860
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1527
ORF Size (bp)
1527 bp
Protein Name (eCommerce)
UBX domain-containing protein 4
RefSeq ID
NM_014607
RefSeq Synonyms
NM_014607, BC035594, BC020806,
Research Areas
Protein Folding
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
UBX domain-containing protein 4 (UBXN4) is Involved in endoplasmic reticulum-associated protein degradation (ERAD). It acts as a platform to recruit both UBQLN1 and VCP to the ER during ERAD (PubMed:19822669) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q92575].
UniGene ID
Hs.591242
UniProt ID (eCommerce)
Q92575

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.