human UBE3C Over-expression AAV

Name 
AAV-h-UBE3C
Cat No 
AAV-227051
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human UBE3C.

AAV-227051
AAV-h-UBE3C

Ready-to-use AAV expressing Human UBE3C (ubiquitin protein ligase E3C). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
HECTH2; HECT-type ubiquitin transferase E3C; ubiquitin-protein isopeptide ligase (E3); ubiquitin-protein ligase E3C
Description (eCommerce)
Ubiquitin protein ligase E3C (UBE3C) is an E3 ubiquitin-protein ligase that accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2D1 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q15386].
Gene ID
9690
Gene Name (eCommerce)
ubiquitin protein ligase E3C
Gene Name (Vector)
ubiquitin protein ligase E3C
Gene Symbol
UBE3C
HGNC ID
HGNC:16803
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1950
ORF Size (bp)
1950 bp
Protein Name (eCommerce)
Ubiquitin-protein ligase E3C
RefSeq ID
NM_014671
RefSeq Synonyms
NM_014671, BC014029,
Research Areas
Antigen Processing and Presentation,Complexome,Immunology,Proteasome,Ubiquitination
Research Areas (Faceted)
cell_biology,immunology
Species
human
Target Sentence
Ubiquitin protein ligase E3C (UBE3C) is an E3 ubiquitin-protein ligase that accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2D1 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q15386].
UniGene ID
Hs.118351
UniProt ID (eCommerce)
Q15386

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.