human UBE2T Over-expression AAV

Name 
AAV-h-UBE2T
Cat No 
AAV-227036
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human UBE2T.

AAV-227036
AAV-h-UBE2T

Ready-to-use AAV expressing Human UBE2T (ubiquitin conjugating enzyme E2 T). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
cell proliferation-inducing gene 50 protein; E2 ubiquitin-conjugating enzyme T; FANCT; HSPC150; HSPC150 protein similar to ubiquitin-conjugating enzyme; PIG50; ubiquitin carrier protein T; ubiquitin conjugating enzyme E2T; ubiquitin-conjugating enzyme E2 T; ubiquitin-conjugating enzyme E2T (putative); ubiquitin-protein ligase T
Description (eCommerce)
Ubiquitin-conjugating enzyme E2 T (UBE2T) is an E2 ubiquitin-conjugating enzyme that is part of the three-step pathway responsible for the covalent attachment of ubiquitin to proteins for their targeted degradation. UBET2 in conjuction with the Fanconi anemia (FA) complex is responsible for the DNA damage-induced monoubiquitination of the FANCD2 protein of the Fanconi Anemia pathway.
Description (Vector)
The covalent conjugation of ubiquitin to proteins regulates diverse cellular pathways and proteins. Ubiquitin is transferred to a target protein through a concerted action of a ubiquitin-activating enzyme (E1), a ubiquitin-conjugating enzyme (E2), such as UBE2T, and a ubiquitin ligase (E3) (Machida et al., 2006 (PubMed 16916645)).(supplied by OMIM, Mar 2008)
Gene ID
29089
Gene Name (eCommerce)
ubiquitin conjugating enzyme E2 T
Gene Name (Vector)
ubiquitin conjugating enzyme E2 T
Gene Symbol
UBE2T
HGNC ID
HGNC:25009
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
594
Protein Name (eCommerce)
Ubiquitin-conjugating enzyme E2 T
RefSeq ID
NM_014176
RefSeq Synonyms
NM_014176, NM_001310326, BC019284, BC004152,
Research Areas
Cancer,DNA Damage/Repair,Fanconi anemia,Ubiquitination
Research Areas (Faceted)
cancer,genetics,transcription_translation,cell_biology,genetics
Species
human
Target Sentence
Ubiquitin-conjugating enzyme E2 T (UBE2T) is an E2 ubiquitin-conjugating enzyme that is part of the three-step pathway responsible for the covalent attachment of ubiquitin to proteins for their targeted degradation. UBET2 in conjuction with the Fanconi anemia (FA) complex is responsible for the DNA damage-induced monoubiquitination of the FANCD2 protein of the Fanconi Anemia pathway.
UniGene ID
Hs.5199
UniProt ID (eCommerce)
Q9NPD8

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.