human UBAC1 Over-expression AAV

Name 
AAV-h-UBAC1
Cat No 
AAV-226969
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human UBAC1.

AAV-226969
AAV-h-UBAC1

Ready-to-use AAV expressing Human UBAC1 (UBA domain containing 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
E3 ubiquitin-protein ligase subunit KPC2; GBDR1; glialblastoma cell differentiation-related protein 1; kip1 ubiquitination-promoting complex protein 2; Kip1 ubiquitination-promoting complex subunit 2; KPC2; putative glialblastoma cell differentiation-related protein; testicular secretory protein Li 64; UBA domain-containing protein 1; UBADC1; ubiquitin associated domain containing 1; ubiquitin-associated domain-containing protein 1
Description (eCommerce)
UBA domain containing 1 (UBAC1) is a non-catalytic subunit of the KPC complex that acts as E3 ubiquitin-protein ligase. UBAC1 is required for poly-ubiquitination and proteasome-mediated degradation of CDKN1B during G1 phase of the cell cycle [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9BSL1].
Gene ID
10422
Gene Name (eCommerce)
UBA domain containing 1
Gene Name (Vector)
UBA domain containing 1
Gene Symbol
UBAC1
HGNC ID
HGNC:30221
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1218
ORF Size (bp)
1218 bp
Protein Name (eCommerce)
Ubiquitin-associated domain-containing protein 1
RefSeq ID
NM_016172
RefSeq Synonyms
NM_016172, BC011822, BC004967,
Research Areas
Golgi Apparatus,Ubiquitination
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
UBA domain containing 1 (UBAC1) is a non-catalytic subunit of the KPC complex that acts as E3 ubiquitin-protein ligase. UBAC1 is required for poly-ubiquitination and proteasome-mediated degradation of CDKN1B during G1 phase of the cell cycle [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9BSL1].
UniGene ID
Hs.9194
UniProt ID (eCommerce)
Q9BSL1

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.