human DSE Over-expression AAV

Name 
AAV-h-DSE
Cat No 
AAV-226658
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human DSE.

AAV-226658
AAV-h-DSE

Ready-to-use AAV expressing Human DSE (dermatan sulfate epimerase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
DS-epi1; DSEP; DSEPI; EDSMC2; SART-2; SART2
Description (Vector)
DSE is a tumor-rejection antigen. This antigen possesses tumor epitopes capable of inducing HLA-A24-restricted and tumor-specific cytotoxic T lymphocytes in cancer patients and may be useful for specific immunotherapy. This gene product is localized to the endoplasmic reticulum. Two transcript variants encoding the same protein have been found for this gene.
Gene ID
29940
Gene Name (Vector)
dermatan sulfate epimerase
Gene Symbol
DSE
HGNC ID
HGNC:21144
ORF Size (aa)
2877
ORF Size (bp)
2877 bp
RefSeq ID
NM_013352
RefSeq Synonyms
NM_013352, NM_001322944, NM_001322943, NM_001322941, NM_001322940, NM_001322939, NM_001322938, NM_001322937, NM_001080976, BC039245,
Species
human
UniGene ID
Hs.486292

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.