human TRIP10 Over-expression AAV

Name 
AAV-h-TRIP10
Cat No 
AAV-226495
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human TRIP10.

AAV-226495
AAV-h-TRIP10

Ready-to-use AAV expressing Human TRIP10 (thyroid hormone receptor interactor 10). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
cdc42-interacting protein 4; CIP4; HSTP; protein Felic; salt tolerant protein; salt tolerator; STOT; STP; thyroid receptor-interacting protein 10; TR-interacting protein 10; TRIP-10
Description (eCommerce)
TRIP10/CIP4 is a multi-functional adapter protein and plays a role in the translocation of Glut4 (glucose transporter) vesicles to the cell surface in response to insulin. TRIP10/CIP4 has also been found to interact with the active GTPases CDC42 and TC10 as well as the Wiskott-Aldrich syndrome protein (WASP), a protein involved in cytoskeletal organization. Recent studies suggest that CIP4 accumulation may play a role in Huntington’s disease pathogenesis.
Gene ID
9322
Gene Name (eCommerce)
thyroid hormone receptor interactor 10
Gene Name (Vector)
thyroid hormone receptor interactor 10
Gene Symbol
TRIP10
HGNC ID
HGNC:12304
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1638
ORF Size (bp)
1638 bp
Protein Name (eCommerce)
Cdc42-interacting protein 4
RefSeq ID
NM_004240
RefSeq Synonyms
NM_004240, NM_001288963, NM_001288962, BC013002,
Research Areas
Cytoskeleton,Golgi Apparatus,Insulin Signaling,Lysosome,Signal Transduction
Research Areas (Faceted)
cell_biology,signal_transduction
Species
human
Target Sentence
TRIP10/CIP4 is a multi-functional adapter protein and plays a role in the translocation of Glut4 (glucose transporter) vesicles to the cell surface in response to insulin. TRIP10/CIP4 has also been found to interact with the active GTPases CDC42 and TC10 as well as the Wiskott-Aldrich syndrome protein (WASP), a protein involved in cytoskeletal organization. Recent studies suggest that CIP4 accumulation may play a role in Huntington’s disease pathogenesis.
UniGene ID
Hs.515094
UniProt ID (eCommerce)
Q15642

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.