human TRIM5 Over-expression AAV

Name 
AAV-h-TRIM5
Cat No 
AAV-226451
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human TRIM5.

AAV-226451
AAV-h-TRIM5

Ready-to-use AAV expressing Human TRIM5 (tripartite motif containing 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
RNF88; TRIM5alpha
Description (Vector)
TRIM5 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein forms homo-oligomers via the coilel-coil region and localizes to cytoplasmic bodies. It appears to function as a E3 ubiquitin-ligase and ubiqutinates itself to regulate its subcellular localization. It may play a role in retroviral restriction. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Gene ID
85363
Gene Name (Vector)
tripartite motif containing 5
Gene Symbol
TRIM5
HGNC ID
HGNC:16276
ORF Size (aa)
1044
RefSeq ID
NM_033034
RefSeq Synonyms
NM_033093, NM_033092, NM_033034, BC021258,
Species
human
UniGene ID
Hs.370515

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.