human TRIM23 Over-expression AAV

Name 
AAV-h-TRIM23
Cat No 
AAV-226413
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human TRIM23.

AAV-226413
AAV-h-TRIM23

Ready-to-use AAV expressing Human TRIM23 (tripartite motif containing 23). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ARD1; ARFD1; RNF46
Description (Vector)
TRIM23 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein is also a member of the ADP ribosylation factor family of guanine nucleotide-binding family of proteins. Its carboxy terminus contains an ADP-ribosylation factor domain and a guanine nucleotide binding site, while the amino terminus contains a GTPase activating protein domain which acts on the guanine nucleotide binding site. The protein localizes to lysosomes and the Golgi apparatus. It plays a role in the formation of intracellular transport vesicles, their movement from one compartment to another, and phopholipase D activation. Three alternatively spliced transcript variants for this gene have been described.
Gene ID
373
Gene Name (Vector)
tripartite motif containing 23
Gene Symbol
TRIM23
HGNC ID
HGNC:660
ORF Size (aa)
1725
ORF Size (bp)
1725 bp
RefSeq ID
NM_001656
RefSeq Synonyms
NM_033228, NM_033227, NM_001656, BC022510,
Species
human
UniGene ID
Hs.792

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.