human TRADD Over-expression AAV

Name 
AAV-h-TRADD
Cat No 
AAV-226319
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human TRADD.

AAV-226319
AAV-h-TRADD

Ready-to-use AAV expressing Human TRADD (TNFRSF1A associated via death domain). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
Hs.89862
Description (Vector)
TRADD is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway.
Gene ID
8717
Gene Name (Vector)
TNFRSF1A associated via death domain
Gene Symbol
TRADD
HGNC ID
HGNC:12030
ORF Size (aa)
939
RefSeq ID
NM_003789
RefSeq Synonyms
NM_003789, NM_001323552, BC004491,
Species
human
UniGene ID
Hs.460996

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.