human TPBG Over-expression AAV

Name 
AAV-h-TPBG
Cat No 
AAV-226243
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human TPBG.

AAV-226243
AAV-h-TPBG

Ready-to-use AAV expressing Human TPBG (trophoblast glycoprotein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
5T4; 5T4AG; M6P1; WAIF1
Description (Vector)
TPBG encodes a leucine-rich transmembrane glycoprotein that may be involved in cell adhesion. The encoded protein is an oncofetal antigen that is specific to trophoblast cells. In adults this protein is highly expressed in many tumor cells and is associated with poor clinical outcome in numerous cancers. Alternate splicing in the 5' UTR results in multiple transcript variants that encode the same protein.
Gene ID
7162
Gene Name (Vector)
trophoblast glycoprotein
Gene Symbol
TPBG
HGNC ID
HGNC:12004
ORF Size (aa)
1263
ORF Size (bp)
1263 bp
RefSeq ID
NM_006670
RefSeq Synonyms
NM_006670, NM_001166392, BC037161,
Species
human
UniGene ID
Hs.82128

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.