human TNK2 Over-expression AAV

Name 
AAV-h-TNK2
Cat No 
AAV-226121
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human TNK2.

AAV-226121
AAV-h-TNK2

Ready-to-use AAV expressing Human TNK2 (tyrosine kinase non receptor 2). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ACK; ACK-1; ACK1; p21cdc42Hs
Description (Vector)
TNK2 encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway. Several alternatively spliced transcript variants have been identified from this gene, but the full-length nature of only two transcript variants has been determined.
Gene ID
10188
Gene Name (Vector)
tyrosine kinase non receptor 2
Gene Symbol
TNK2
HGNC ID
HGNC:19297
ORF Size (aa)
3117
ORF Size (bp)
3117 bp
RefSeq ID
NM_005781
RefSeq Synonyms
NM_005781, NM_001308046, NM_001010938, BC156798, BC028164,
Species
human
UniGene ID
Hs.518513

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.