human TMX1 Over-expression AAV

Name 
AAV-h-TMX1
Cat No 
AAV-226047
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human TMX1.

AAV-226047
AAV-h-TMX1

Ready-to-use AAV expressing Human TMX1 (thioredoxin related transmembrane protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
PDIA11; protein disulfide isomerase family A, member 11; thioredoxin domain containing 1; thioredoxin domain-containing protein 1; thioredoxin-related transmembrane protein 1; TMX; transmembrane Trx-related protein; TXNDC; TXNDC1
Description (eCommerce)
Thioredoxin-related transmembrane protein 1 (TMX1) may participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9H3N1].
Description (Vector)
TXNDC1 is a thioredoxin (TXN; see MIM 187700)-related protein with disulfide reductase activity (Matsuo et al., 2001 (PubMed 11152479)).(supplied by OMIM, Mar 2008)
Gene ID
81542
Gene Name (eCommerce)
thioredoxin related transmembrane protein 1
Gene Name (Vector)
thioredoxin related transmembrane protein 1
Gene Symbol
TMX1
HGNC ID
HGNC:15487
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
843
Protein Name (eCommerce)
Thioredoxin-related transmembrane protein 1
RefSeq ID
NM_030755
RefSeq Synonyms
NM_030755, BC056874, BC036460,
Research Areas
Apoptosis,Cell Cycle,DNA Replication,Golgi Apparatus,Immunology,Replication,Signal Transduction,Transcription Factor/Regulator
Research Areas (Faceted)
signal_transduction,cell_biology,cell_cycle,genetics,transcription_translation,cell_biology,immunology,cell_biology,cell_cycle,genetics,transcription_translation
Species
human
Target Sentence
Thioredoxin-related transmembrane protein 1 (TMX1) may participate in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyze dithiol-disulfide exchange reactions [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9H3N1].
UniGene ID
Hs.125221
UniProt ID (eCommerce)
Q9H3N1

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.