human THRA Over-expression AAV

Name 
AAV-h-THRA
Cat No 
AAV-225466
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human THRA.

AAV-225466
AAV-h-THRA

Ready-to-use AAV expressing Human THRA (thyroid hormone receptor, alpha). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
AR7; c-ERBA-1; CHNG6; EAR7; ERB-T-1; ERBA; ERBA1; NR1A1; THRA1; THRA2
Description (Vector)
THRA is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Gene ID
7067
Gene Name (Vector)
thyroid hormone receptor, alpha
Gene Symbol
THRA
HGNC ID
HGNC:11796
ORF Size (aa)
1356
ORF Size (bp)
1356 bp
RefSeq ID
NM_003250
RefSeq Synonyms
NM_199334, NM_003250, NM_001190919, NM_001190918, BC035137, BC008851, BC002728, BC000261,
Species
human
UniGene ID
Hs.724

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.