human TCERG1 Over-expression AAV

Name 
AAV-h-TCERG1
Cat No 
AAV-225200
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human TCERG1.

AAV-225200
AAV-h-TCERG1

Ready-to-use AAV expressing Human TCERG1 (transcription elongation regulator 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CA150; co-activator of 150 kDa; TAF2S; TATA box binding protein (TBP)-associated factor, RNA polymerase II, S, 150kD; TATA box-binding protein-associated factor 2S; transcription elongation regulator 1; transcription factor CA150; Urn1
Description (eCommerce)
CA150 has been identified as a transcriptional cofactor that functions as a corepressor of Tat-activated and C/EBP-activated gene transcription. CA150 also has been shown to interact with RNA polymerase II and the splicing factor SF1 to function in transcription elongation and pre-mRNA splicing.
Description (Vector)
TCERG1 encodes a nuclear protein that regulates transcriptional elongation and pre-mRNA splicing. The encoded protein interacts with the hyperphosphorylated C-terminal domain of RNA polymerase II via multiple FF domains, and with the pre-mRNA splicing factor SF1 via a WW domain. Alternative splicing results in multiple transcripts variants encoding different isoforms.
Gene ID
10915
Gene Name (eCommerce)
transcription elongation regulator 1
Gene Name (Vector)
transcription elongation regulator 1
Gene Symbol
TCERG1
HGNC ID
HGNC:15630
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3234
ORF Size (bp)
3234 bp
Protein Name (eCommerce)
Transcription elongation regulator 1
RefSeq ID
NM_006706
RefSeq Synonyms
NM_006706, NM_001040006, BC111727,
Research Areas
Gene Expression,Nuclear Receptor Coactivators,RNA Processing,Spliceosome,Transcription Factor/Regulator
Research Areas (Faceted)
genetics,transcription_translation,cell_biology
Species
human
Target Sentence
CA150 has been identified as a transcriptional cofactor that functions as a corepressor of Tat-activated and C/EBP-activated gene transcription. CA150 also has been shown to interact with RNA polymerase II and the splicing factor SF1 to function in transcription elongation and pre-mRNA splicing.
UniGene ID
Hs.443465
UniProt ID (eCommerce)
O14776

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.