human TCERG1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human TCERG1.
shADV-225200
Ad-h-TCERG1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human TCERG1 (transcription elongation regulator 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CA150; co-activator of 150 kDa; TAF2S; TATA box binding protein (TBP)-associated factor, RNA polymerase II, S, 150kD; TATA box-binding protein-associated factor 2S; transcription elongation regulator 1; transcription factor CA150; Urn1
Description (eCommerce)
CA150 has been identified as a transcriptional cofactor that functions as a corepressor of Tat-activated and C/EBP-activated gene transcription. CA150 also has been shown to interact with RNA polymerase II and the splicing factor SF1 to function in transcription elongation and pre-mRNA splicing.
Description (Vector)
TCERG1 encodes a nuclear protein that regulates transcriptional elongation and pre-mRNA splicing. The encoded protein interacts with the hyperphosphorylated C-terminal domain of RNA polymerase II via multiple FF domains, and with the pre-mRNA splicing factor SF1 via a WW domain. Alternative splicing results in multiple transcripts variants encoding different isoforms.
Gene ID
10915
Gene Name (eCommerce)
transcription elongation regulator 1
Gene Name (Vector)
transcription elongation regulator 1
Gene Symbol
TCERG1
HGNC ID
HGNC:15630
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
3234
ORF Size (bp)
3234 bp
Protein Name (eCommerce)
Transcription elongation regulator 1
RefSeq ID
NM_006706
RefSeq Synonyms
NM_006706, NM_001040006, BC111727,
Research Areas
Gene Expression,Nuclear Receptor Coactivators,RNA Processing,Spliceosome,Transcription Factor/Regulator
Research Areas (Faceted)
genetics,transcription_translation,cell_biology
Species
human
Target Sentence
CA150 has been identified as a transcriptional cofactor that functions as a corepressor of Tat-activated and C/EBP-activated gene transcription. CA150 also has been shown to interact with RNA polymerase II and the splicing factor SF1 to function in transcription elongation and pre-mRNA splicing.
UniGene ID
Hs.443465
UniProt ID (eCommerce)
O14776
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.