human TBC1D2 Over-expression AAV

Name
AAV-h-TBC1D2

Cat No
AAV-225077

Availability
4-5 weeks

This is an AAV expressing Human TBC1D2.

AAV-225077

AAV-h-TBC1D2

Ready-to-use AAV expressing Human TBC1D2 (TBC1 domain family member 2). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

armus; PARIS1; PARIS-1; prostate antigen recognized and identified by SEREX 1; TBC1 domain family member 2A; TBC1 domain family, member 2A; TBC1D2A

Description (eCommerce)

TBC1 domain family member 2A (TBC1D2) acts as GTPase-activating protein for RAB7A. TBC1D2 is a signal effector acting as a linker between RAC1 and RAB7A, leading to RAB7A inactivation and subsequent inhibition of cadherin degradation and reduced cell-cell adhesion [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q9BYX2].

Gene ID

55357

Gene Name (eCommerce)

TBC1 domain family member 2

Gene Name (Vector)

TBC1 domain family member 2

Gene Symbol

TBC1D2

HGNC ID

HGNC:18026

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

1509

ORF Size (bp)

1509 bp

Protein Name (eCommerce)

TBC1 domain family member 2A

RefSeq ID

NM_018421

RefSeq Synonyms

NM_018421, NM_001267572, NM_001267571, BC071978, BC028918,

Research Areas

Cytoskeleton,Signal Transduction

Research Areas (Faceted)

signal_transduction,cell_biology

Species

human

Target Sentence

TBC1 domain family member 2A (TBC1D2) acts as GTPase-activating protein for RAB7A. TBC1D2 is a signal effector acting as a linker between RAC1 and RAB7A, leading to RAB7A inactivation and subsequent inhibition of cadherin degradation and reduced cell-cell adhesion [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q9BYX2].

UniGene ID

Hs.371016

UniProt ID (eCommerce)

Q9BYX2

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.