human TBC1D2 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human TBC1D2.
shAAV-225078
AAV-h-TBC1D2-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human TBC1D2 (TBC1 domain family member 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
armus; PARIS1; PARIS-1; prostate antigen recognized and identified by SEREX 1; TBC1 domain family member 2A; TBC1 domain family, member 2A; TBC1D2A
Description (eCommerce)
TBC1 domain family member 2A (TBC1D2) acts as GTPase-activating protein for RAB7A. TBC1D2 is a signal effector acting as a linker between RAC1 and RAB7A, leading to RAB7A inactivation and subsequent inhibition of cadherin degradation and reduced cell-cell adhesion [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q9BYX2].
Gene ID
55357
Gene Name (eCommerce)
TBC1 domain family member 2
Gene Name (Vector)
TBC1 domain family member 2
Gene Symbol
TBC1D2
HGNC ID
HGNC:18026
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1509
ORF Size (bp)
1509 bp
Protein Name (eCommerce)
TBC1 domain family member 2A
RefSeq ID
NM_018421
RefSeq Synonyms
NM_018421, NM_001267572, NM_001267571, BC071978, BC028918,
Research Areas
Cytoskeleton,Signal Transduction
Research Areas (Faceted)
signal_transduction,cell_biology
Species
human
Target Sentence
TBC1 domain family member 2A (TBC1D2) acts as GTPase-activating protein for RAB7A. TBC1D2 is a signal effector acting as a linker between RAC1 and RAB7A, leading to RAB7A inactivation and subsequent inhibition of cadherin degradation and reduced cell-cell adhesion [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q9BYX2].
UniGene ID
Hs.371016
UniProt ID (eCommerce)
Q9BYX2
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.