human TAZ Over-expression AAV

Name 
AAV-h-TAZ
Cat No 
AAV-225052
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human TAZ.

AAV-225052
AAV-h-TAZ

Ready-to-use AAV expressing Human TAZ (tafazzin). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
BTHS; CMD3A; EFE; EFE2; G4.5; LVNCX; Taz1
Description (Vector)
TAZ encodes a protein that is expressed at high levels in cardiac and skeletal muscle. Mutations in this gene have been associated with a number of clinical disorders including Barth syndrome, dilated cardiomyopathy (DCM), hypertrophic DCM, endocardial fibroelastosis, and left ventricular noncompaction (LVNC). Multiple transcript variants encoding different isoforms have been described. A long form and a short form of each of these isoforms is produced; the short form lacks a hydrophobic leader sequence and may exist as a cytoplasmic protein rather than being membrane-bound. Other alternatively spliced transcripts have been described but the full-length nature of all these transcripts is not known.
Gene ID
6901
Gene Name (Vector)
tafazzin
Gene Symbol
TAZ
HGNC ID
HGNC:11577
ORF Size (aa)
789
RefSeq ID
NM_000116
RefSeq Synonyms
NM_181313, NM_181312, NM_181311, NM_001303465, NM_000116, BC011515,
Species
human
UniGene ID
Hs.409911

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.