human TARS Over-expression AAV

Name 
AAV-h-TARS
Cat No 
AAV-224975
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human TARS.

AAV-224975
AAV-h-TARS

Ready-to-use AAV expressing Human TARS (threonyl-tRNA synthetase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
threonine tRNA ligase 1, cytoplasmic; threonine--tRNA ligase, cytoplasmic; Threonyl-tRNA synthetase; threonyl-tRNA synthetase, cytoplasmic; ThrRS
Description (eCommerce)
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Threonyl-tRNA synthetase (TARS) belongs to the class-II aminoacyl-tRNA synthetase family [taken from NCBI Entrez Gene (Gene ID: 6897)].
Description (Vector)
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Threonyl-tRNA synthetase belongs to the class-II aminoacyl-tRNA synthetase family
Gene ID
6897
Gene Name (eCommerce)
threonyl-tRNA synthetase
Gene Name (Vector)
threonyl-tRNA synthetase
Gene Symbol
TARS
HGNC ID
HGNC:11572
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2172
ORF Size (bp)
2172 bp
Protein Name (eCommerce)
Threonine--tRNA ligase, cytoplasmic
RefSeq ID
NM_152295
RefSeq Synonyms
NM_152295, NM_001258438, NM_001258437, BC010578, BC000517,
Research Areas
Cytoskeleton,Gene Expression,Translational Control
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Threonyl-tRNA synthetase (TARS) belongs to the class-II aminoacyl-tRNA synthetase family [taken from NCBI Entrez Gene (Gene ID: 6897)].
UniGene ID
Hs.481860
UniProt ID (eCommerce)
P26639

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.