human TAPBP Over-expression AAV
This is an AAV expressing Human TAPBP.
AAV-224968
AAV-h-TAPBP
Ready-to-use AAV expressing Human TAPBP (TAP binding protein). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
NGS17; TAPA; TPN; TPSN
Description (Vector)
TAPBP encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. TAPBP lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms.
Gene ID
6892
Gene Name (Vector)
TAP binding protein
Gene Symbol
TAPBP
HGNC ID
HGNC:11566
ORF Size (aa)
1515
ORF Size (bp)
1515 bp
RefSeq ID
NM_003190
RefSeq Synonyms
NM_172209, NM_172208, NM_003190, BC080574,
Species
human
UniGene ID
Hs.714746
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.