human TAF1C Over-expression AAV

Name 
AAV-h-TAF1C
Cat No 
AAV-224918
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human TAF1C.

AAV-224918
AAV-h-TAF1C

Ready-to-use AAV expressing Human TAF1C (TATA-box binding protein associated factor, RNA polymerase I subunit C). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
MGC:39976; RNA polymerase I-specific TBP-associated factor 110 kDa; SL1; SL1, 110kD subunit; TAFI110; TAFI95; TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kD; TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa; TATA box-binding protein-associated factor 1C; TATA box-binding protein-associated factor RNA polymerase I subunit C; TATA-box binding protein associated factor, RNA polymerase I, C; TBP-associated factor 1C; transcription factor SL1; transcription initiation factor SL1/TIF-IB subunit C
Description (eCommerce)
TATA box-binding protein-associated factor RNA polymerase I subunit C (TAF1C) is a component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q15572].
Description (Vector)
Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated factors (TAFs) specific for RNA polymerase I. This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals. This gene encodes the largest SL1-specific TAF. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
Gene ID
9013
Gene Name (eCommerce)
TATA-box binding protein associated factor, RNA polymerase I subunit C
Gene Name (Vector)
TATA-box binding protein associated factor, RNA polymerase I subunit C
Gene Symbol
TAF1C
HGNC ID
HGNC:11534
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2328
ORF Size (bp)
2328 bp
Protein Name (eCommerce)
TATA box-binding protein-associated factor RNA polymerase I subunit C
RefSeq ID
NM_005679
RefSeq Synonyms
NM_139353, NM_005679, NM_001243160, NM_001243159, NM_001243158, NM_001243157, NM_001243156, BC028131,
Research Areas
Epigenetic Regulation of Gene Expression,Gene Expression,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,genetics,transcription_translation
Species
human
Target Sentence
TATA box-binding protein-associated factor RNA polymerase I subunit C (TAF1C) is a component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q15572].
UniGene ID
Hs.153022
UniProt ID (eCommerce)
Q15572

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.