human SURF1 Over-expression AAV

Name 
AAV-h-SURF1
Cat No 
AAV-224757
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human SURF1.

AAV-224757
AAV-h-SURF1

Ready-to-use AAV expressing Human SURF1 (SURF1, cytochrome c oxidase assembly factor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
CMT4K
Description (Vector)
SURF1 encodes a protein localized to the inner mitochondrial membrane and thought to be involved in the biogenesis of the cytochrome c oxidase complex. The protein is a member of the SURF1 family, which includes the related yeast protein SHY1 and rickettsial protein RP733. The gene is located in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity, where it shares a bidirectional promoter with SURF2 on the opposite strand. Defects in this gene are a cause of Leigh syndrome, a severe neurological disorder that is commonly associated with systemic cytochrome c oxidase deficiency.
Gene ID
6834
Gene Name (Vector)
SURF1, cytochrome c oxidase assembly factor
Gene Symbol
SURF1
HGNC ID
HGNC:11474
ORF Size (aa)
903
RefSeq ID
NM_003172
RefSeq Synonyms
NM_003172, NM_001280787, BC071658, BC028314,
Species
human
UniGene ID
Hs.512464

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.