human SULF1 Over-expression AAV

Name 
AAV-h-SULF1
Cat No 
AAV-224702
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human SULF1.

AAV-224702
AAV-h-SULF1

Ready-to-use AAV expressing Human SULF1 (sulfatase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
SULF-1
Description (Vector)
Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF1, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai et al., 2005 (PubMed 16192265)).(supplied by OMIM, Mar 2008)
Gene ID
23213
Gene Name (Vector)
sulfatase 1
Gene Symbol
SULF1
HGNC ID
HGNC:20391
ORF Size (aa)
1935
ORF Size (bp)
1935 bp
RefSeq ID
NM_015170
RefSeq Synonyms
NM_015170, NM_001128206, NM_001128205, NM_001128204, BC068565,
Species
human
UniGene ID
Hs.409602

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.