human STXBP1 Over-expression AAV

Name
AAV-h-STXBP1

Cat No
AAV-224672

Availability
4-5 weeks

This is an AAV expressing Human STXBP1.

AAV-224672

AAV-h-STXBP1

Ready-to-use AAV expressing Human STXBP1 (syntaxin binding protein 1). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

MUNC18-1; neuronal SEC1; NSEC1; N-Sec1; P67; protein unc-18 homolog 1; protein unc-18 homolog A; RBSEC1; syntaxin-binding protein 1; UNC18; unc18-1; unc-18A

Description (eCommerce)

Syntaxin-binding protein 1 (STXBP1) is a syntaxin-binding protein. STXBP1 appears to play a role in release of neurotransmitters via regulation of syntaxin, a transmembrane attachment protein receptor [taken from NCBI Entrez Gene (Gene ID: 6812)].

Description (Vector)

STXBP1 encodes a syntaxin-binding protein. The encoded protein appears to play a role in release of neurotransmitters via regulation of syntaxin, a transmembrane attachment protein receptor. Mutations in this gene have been associated with infantile epileptic encephalopathy-4. Alternatively spliced transcript variants have been described.

Gene ID

6812

Gene Name (eCommerce)

syntaxin binding protein 1

Gene Name (Vector)

syntaxin binding protein 1

Gene Symbol

STXBP1

HGNC ID

HGNC:11444

NCBI Taxonomy ID (eCommerce)

9606.0

ORF Size (aa)

1785

ORF Size (bp)

1785 bp

Protein Name (eCommerce)

Syntaxin-binding protein 1

RefSeq ID

NM_003165

RefSeq Synonyms

NM_003165, NM_001032221, BC015749,

Research Areas

Apoptosis,EGFR Signaling,Epilepsy,Insulin Signaling,Metabolism/Metabolic Process,Mitochondrion,Neurobiology,Neurodevelopment,Signal Transduction

Research Areas (Faceted)

signal_transduction,cell_biology,neurobiology,signal_transduction,metabolism,cell_biology,neurobiology,developmental_biology

Species

human

Target Sentence

UniGene ID

Hs.288229

UniProt ID (eCommerce)

P61764

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.