human ST3GAL3 Over-expression AAV

Name 
AAV-h-ST3GAL3
Cat No 
AAV-224459
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human ST3GAL3.

AAV-224459
AAV-h-ST3GAL3

Ready-to-use AAV expressing Human ST3GAL3 (ST3 beta-galactoside alpha-2,3-sialyltransferase 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
EIEE15; MRT12; SIAT6; ST3GALII; ST3GalIII; ST3N
Description (Vector)
ST3GAL3 is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein is normally found in the Golgi apparatus but can be proteolytically processed to a soluble form. This protein is a member of glycosyltransferase family 29. Mutations in this gene have been associated with autosomal recessive nonsymdromic mental retardation-12 (MRT12). Multiple transcript variants encoding several different isoforms have been found for this gene.
Gene ID
6487
Gene Name (Vector)
ST3 beta-galactoside alpha-2,3-sialyltransferase 3
Gene Symbol
ST3GAL3
HGNC ID
HGNC:10866
ORF Size (aa)
1128
ORF Size (bp)
1128 bp
RefSeq ID
NM_006279
RefSeq Synonyms
NM_174971, NM_174970, NM_174969, NM_174968, NM_174967, NM_174966, NM_174965, NM_174964, NM_174963, NM_006279, NM_001270466, NM_001270465, NM_001270464, NM_001270463, NM_001270462, NM_001270461, NM_001270460, NM_001270459, BC050380,
Species
human
UniGene ID
Hs.597915

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.