human SPP1 Over-expression AAV
This is an AAV expressing Human SPP1.
AAV-224230
AAV-h-SPP1
Ready-to-use AAV expressing Human SPP1 (secreted phosphoprotein 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BNSP; BSPI; ETA-1; OPN
Description (Vector)
SPP1 is involved in the attachment of osteoclasts to the mineralized bone matrix. The encoded protein is secreted and binds hydroxyapatite with high affinity. The osteoclast vitronectin receptor is found in the cell membrane and may be involved in the binding to this protein. This protein is also a cytokine that upregulates expression of interferon-gamma and interleukin-12. Several transcript variants encoding different isoforms have been found for this gene.
Gene ID
6696
Gene Name (Vector)
secreted phosphoprotein 1
Gene Symbol
SPP1
HGNC ID
HGNC:11255
ORF Size (aa)
864
RefSeq ID
NM_000582
RefSeq Synonyms
NM_001251830, NM_001251829, NM_001040060, NM_001040058, NM_000582, BC093033, BC022844, BC017387, BC007016,
Species
human
UniGene ID
Hs.313
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.