human SMPD2 Over-expression AAV

Name 
AAV-h-SMPD2
Cat No 
AAV-223768
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human SMPD2.

AAV-223768
AAV-h-SMPD2

Ready-to-use AAV expressing Human SMPD2 (sphingomyelin phosphodiesterase 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ISC1; NSMASE; NSMASE1
Description (Vector)
SMPD2 encodes a protein which was initially identified as a sphingomyelinase based on sequence similarity between bacterial sphingomyelinases and a yeast protein. Subsequent studies showed that its biological function is less likely to be as a sphingomyelinase and instead as a lysophospholipase.
Gene ID
6610
Gene Name (Vector)
sphingomyelin phosphodiesterase 2
Gene Symbol
SMPD2
HGNC ID
HGNC:11121
ORF Size (aa)
1272
ORF Size (bp)
1272 bp
RefSeq ID
NM_003080
RefSeq Synonyms
NM_003080, BC000038,
Species
human
UniGene ID
Hs.55235

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.