human SMCR7 Over-expression AAV

Name 
AAV-h-SMCR7
Cat No 
AAV-223743
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human MIEF2.

AAV-223743
AAV-h-SMCR7

Ready-to-use AAV expressing Human MIEF2 (mitochondrial elongation factor 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
MID49; SMCR7
Description (Vector)
SMCR7 encodes an outer mitochondrial membrane protein that functions in the regulation of mitochondrial morphology. It can directly recruit the fission mediator dynamin-related protein 1 (Drp1) to the mitochondrial surface. The gene is located within the Smith-Magenis syndrome region on chromosome 17. Alternative splicing results in multiple transcript variants encoding different isoforms.
Gene ID
125170
Gene Name (Vector)
mitochondrial elongation factor 2
Gene Symbol
MIEF2
HGNC ID
HGNC:17920
ORF Size (aa)
1365
ORF Size (bp)
1365 bp
RefSeq ID
NM_139162
RefSeq Synonyms
NM_148886, NM_139162, NM_001144900, BC014973,
Species
human
UniGene ID
Hs.655555

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.