human SLITRK5 Over-expression AAV

Name 
AAV-h-SLITRK5
Cat No 
AAV-223663
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human SLITRK5.

AAV-223663
AAV-h-SLITRK5

Ready-to-use AAV expressing Human SLITRK5 (SLIT and NTRK like family member 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
bA364G4.2; leucine rich repeat containing 11; leucine-rich repeat-containing protein 11; LRRC11; SLIT and NTRK-like protein 5; slit and trk like gene 5
Description (eCommerce)
Members of the SLITRK family, such as SLITRK5, are integral membrane proteins with 2 N-terminal leucine-rich repeat (LRR) domains similar to those of SLIT proteins. Most SLITRKs, including SLITRK5, also have C-terminal regions that share homology with neurotrophin receptors. SLITRKs are expressed predominantly in neural tissues and have neurite-modulating activity (Aruga et al., 2003 [PubMed 14557068]) [taken from NCBI Entrez Gene (Gene ID: 26050)].
Description (Vector)
Members of the SLITRK family, such as SLITRK5, are integral membrane proteins with 2 N-terminal leucine-rich repeat (LRR) domains similar to those of SLIT proteins (see SLIT1; MIM 603742). Most SLITRKs, including SLITRK5, also have C-terminal regions that share homology with neurotrophin receptors (see NTRK1; MIM 191315). SLITRKs are expressed predominantly in neural tissues and have neurite-modulating activity (Aruga et al., 2003 (PubMed 14557068)).(supplied by OMIM, Mar 2008)
Gene ID
26050
Gene Name (eCommerce)
SLIT and NTRK like family member 5
Gene Name (Vector)
SLIT and NTRK like family member 5
Gene Symbol
SLITRK5
HGNC ID
HGNC:20295
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2877
ORF Size (bp)
2877 bp
Protein Name (eCommerce)
SLIT and NTRK-like protein 5
RefSeq ID
NM_015567
RefSeq Synonyms
NM_015567, BC103509, BC098287, BC098106,
Research Areas
Axonogenesis,Neurobiology,Signal Transduction
Research Areas (Faceted)
signal_transduction,neurobiology,developmental_biology,neurobiology
Species
human
Target Sentence
Members of the SLITRK family, such as SLITRK5, are integral membrane proteins with 2 N-terminal leucine-rich repeat (LRR) domains similar to those of SLIT proteins. Most SLITRKs, including SLITRK5, also have C-terminal regions that share homology with neurotrophin receptors. SLITRKs are expressed predominantly in neural tissues and have neurite-modulating activity (Aruga et al., 2003 [PubMed 14557068]) [taken from NCBI Entrez Gene (Gene ID: 26050)].
UniGene ID
Hs.591208
UniProt ID (eCommerce)
O94991

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.