human SLC6A2 Over-expression AAV

Name
AAV-h-SLC6A2

Cat No
AAV-223565

Availability
4-5 weeks

This is an AAV expressing Human SLC6A2.

AAV-223565

AAV-h-SLC6A2

Ready-to-use AAV expressing Human SLC6A2 (solute carrier family 6 member 2). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

NAT1; NET; NET1; SLC6A5

Description (Vector)

SLC6A2 encodes a member of the sodium:neurotransmitter symporter family. This member is a multi-pass membrane protein, which is responsible for reuptake of norepinephrine into presynaptic nerve terminals and is a regulator of norepinephrine homeostasis. Mutations in this gene cause orthostatic intolerance, a syndrome characterized by lightheadedness, fatigue, altered mentation and syncope. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.

Gene ID

6530

Gene Name (Vector)

solute carrier family 6 member 2

Gene Symbol

SLC6A2

HGNC ID

HGNC:11048

ORF Size (aa)

1854

ORF Size (bp)

1854 bp

RefSeq ID

NM_001043

RefSeq Synonyms

NM_001172504, NM_001172502, NM_001172501, NM_001043, BC156903,

Species

human

UniGene ID

Hs.78036

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.