human SLC6A5 Over-expression AAV

Name 
AAV-h-SLC6A5
Cat No 
AAV-223571
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human SLC6A5.

AAV-223571
AAV-h-SLC6A5

Ready-to-use AAV expressing Human SLC6A5 (solute carrier family 6 member 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
GLYT-2; GLYT2; HKPX3; NET1
Description (Vector)
SLC6A5 encodes a sodium- and chloride-dependent glycine neurotransmitter transporter. This integral membrane glycoprotein is responsible for the clearance of extracellular glycine during glycine-mediated neurotransmission. This protein is found in glycinergic axons and maintains a high presynaptic pool of neurotransmitter at glycinergic synapses. Mutations in this gene cause hyperekplexia; a heterogenous neurological disorder characterized by exaggerated startle responses and neonatal apnea.
Gene ID
9152
Gene Name (Vector)
solute carrier family 6 member 5
Gene Symbol
SLC6A5
HGNC ID
HGNC:11051
ORF Size (aa)
2394
ORF Size (bp)
2394 bp
RefSeq ID
NM_004211
RefSeq Synonyms
NM_004211, NM_001318369, BC096321, BC096320, BC096319,
Species
human
UniGene ID
Hs.136557

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.