human SLC26A5 Over-expression AAV

Name 
AAV-h-SLC26A5
Cat No 
AAV-223305
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human SLC26A5.

AAV-223305
AAV-h-SLC26A5

Ready-to-use AAV expressing Human SLC26A5 (solute carrier family 26 member 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
DFNB61; PRES
Description (Vector)
SLC26A5 encodes a member of the SLC26A/SulP transporter family. The protein functions as a molecular motor in motile outer hair cells (OHCs) of the cochlea, inducing changes in cell length that act to amplify sound levels. The transmembrane protein is an incomplete anion transporter, and does not allow anions to cross the cell membrane but instead undergoes a conformational change in response to changes in intracellular Cl- levels that results in a change in cell length. The protein functions at microsecond rates, which is several orders of magnitude faster than conventional molecular motor proteins. Mutations in this gene are potential candidates for causing neurosensory deafness. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
375611
Gene Name (Vector)
solute carrier family 26 member 5
Gene Symbol
SLC26A5
HGNC ID
HGNC:9359
ORF Size (aa)
2139
ORF Size (bp)
2139 bp
RefSeq ID
NM_198999
RefSeq Synonyms
NM_206885, NM_206884, NM_206883, NM_198999, NM_001321787, NM_001167962, BC100835, BC100833, BC100832,
Species
human
UniGene ID
Hs.585146

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.