human SH2B3 Over-expression AAV
This is an AAV expressing Human SH2B3.
AAV-222878
AAV-h-SH2B3
Ready-to-use AAV expressing Human SH2B3 (SH2B adaptor protein 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
IDDM20; LNK
Description (Vector)
SH2B3 encodes a member of the SH2B adaptor family of proteins, which are involved in a range of signaling activities by growth factor and cytokine receptors. The encoded protein is a key negative regulator of cytokine signaling and plays a critical role in hematopoiesis. Mutations in this gene have been associated with susceptibility to celiac disease type 13 and susceptibility to insulin-dependent diabetes mellitus.
Gene ID
10019
Gene Name (Vector)
SH2B adaptor protein 3
Gene Symbol
SH2B3
HGNC ID
HGNC:29605
ORF Size (aa)
1728
ORF Size (bp)
1728 bp
RefSeq ID
NM_005475
RefSeq Synonyms
NM_005475, NM_001291424, BC136451, BC015786,
Species
human
UniGene ID
Hs.506784
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.