human SGPP1 Over-expression AAV

Name 
AAV-h-SGPP1
Cat No 
AAV-222866
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human SGPP1.

AAV-222866
AAV-h-SGPP1

Ready-to-use AAV expressing Human SGPP1 (sphingosine-1-phosphate phosphatase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
SPPase1
Description (Vector)
Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid metabolite that regulates diverse biologic processes. SGPP1 catalyzes the degradation of S1P via salvage and recycling of sphingosine into long-chain ceramides (Mandala et al., 2000 (PubMed 10859351); Le Stunff et al., 2007 (PubMed 17895250)).(supplied by OMIM, Jun 2009)
Gene ID
81537
Gene Name (Vector)
sphingosine-1-phosphate phosphatase 1
Gene Symbol
SGPP1
HGNC ID
HGNC:17720
ORF Size (aa)
1326
ORF Size (bp)
1326 bp
RefSeq ID
NM_030791
RefSeq Synonyms
NM_030791, BC070060, BC063839,
Species
human
UniGene ID
Hs.24678

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.