human SERPING1 Over-expression AAV

Name 
AAV-h-SERPING1
Cat No 
AAV-222710
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human SERPING1.

AAV-222710
AAV-h-SERPING1

Ready-to-use AAV expressing Human SERPING1 (serpin family G member 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
C1IN; C1INH; C1NH; HAE1; HAE2
Description (Vector)
SERPING1 encodes a highly glycosylated plasma protein involved in the regulation of the complement cascade. Its protein inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. Deficiency of this protein is associated with hereditary angioneurotic oedema (HANE). Alternative splicing results in multiple transcript variants encoding the same isoform.
Gene ID
710
Gene Name (Vector)
serpin family G member 1
Gene Symbol
SERPING1
HGNC ID
HGNC:1228
ORF Size (aa)
1503
ORF Size (bp)
1503 bp
RefSeq ID
NM_000062
RefSeq Synonyms
NM_001032295, NM_000062, BC011171,
Species
human
UniGene ID
Hs.384598

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.