human SERPINA7 Over-expression AAV

Name 
AAV-h-SERPINA7
Cat No 
AAV-222678
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human SERPINA7.

AAV-222678
AAV-h-SERPINA7

Ready-to-use AAV expressing Human SERPINA7 (serpin family A member 7). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
TBG; TBGQTL
Description (Vector)
There are three proteins including thyroxine-binding globulin (TBG), transthyretin and albumin responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3'-triiodothyronine (T3) in the bloodstream. This gene encodes the major thyroid hormone transport protein, TBG, in serum. It belongs to the serpin family in genomics, but the protein has no inhibitory function like many other members of the serpin family. Mutations in this gene result in TGB deficiency, which has been classified as partial deficiency, complete deficiency, and excess, based on the level of serum TBG. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined.
Gene ID
6906
Gene Name (Vector)
serpin family A member 7
Gene Symbol
SERPINA7
HGNC ID
HGNC:11583
ORF Size (aa)
1248
ORF Size (bp)
1248 bp
RefSeq ID
NM_000354
RefSeq Synonyms
NM_000354, BC020747,
Species
human
UniGene ID
Hs.76838

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.