human SERPINA7 shRNA silencing AAV
This is an AAV expressing shRNA for silencing of Human SERPINA7.
shAAV-222678
AAV-h-SERPINA7-shRNA
Ready-to-use AAV expressing shRNA for silencing of Human SERPINA7 (serpin family A member 7). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
TBG; TBGQTL
Description (Vector)
There are three proteins including thyroxine-binding globulin (TBG), transthyretin and albumin responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3'-triiodothyronine (T3) in the bloodstream. This gene encodes the major thyroid hormone transport protein, TBG, in serum. It belongs to the serpin family in genomics, but the protein has no inhibitory function like many other members of the serpin family. Mutations in this gene result in TGB deficiency, which has been classified as partial deficiency, complete deficiency, and excess, based on the level of serum TBG. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined.
Gene ID
6906
Gene Name (Vector)
serpin family A member 7
Gene Symbol
SERPINA7
HGNC ID
HGNC:11583
ORF Size (aa)
1248
ORF Size (bp)
1248 bp
RefSeq ID
NM_000354
RefSeq Synonyms
NM_000354, BC020747,
Species
human
UniGene ID
Hs.76838
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.