human SEMA3E Over-expression AAV

Name
AAV-h-SEMA3E

Cat No
AAV-222542

Availability
4-5 weeks

This is an AAV expressing Human SEMA3E.

AAV-222542

AAV-h-SEMA3E

Ready-to-use AAV expressing Human SEMA3E (semaphorin 3E). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

AAV ITR

AAV2

Promoter

CMV (default), or choose from 30 different ubiquitous or cell specific promoter

Reporter

none, optional GFP, CFP, YFP, RFP or mCherry

Storage Buffer

PBS/5% Glycerol

Viral Backbone

Recombinant AAV

Gene Reference Data

Alternate Names

coll-5; M-SEMAH; M-SemaK; SEMAH

Description (Vector)

Semaphorins are a large family of conserved secreted and membrane associated proteins which possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Based on sequence and structural similarities, semaphorins are put into eight classes: invertebrates contain classes 1 and 2, viruses have class V, and vertebrates contain classes 3-7. Semaphorins serve as axon guidance ligands via multimeric receptor complexes, some (if not all) containing plexin proteins. This gene encodes a class 4 semaphorin. This gene encodes a class 3 semaphorin. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene ID

9723

Gene Name (Vector)

semaphorin 3E

Gene Symbol

SEMA3E

HGNC ID

HGNC:10727

ORF Size (aa)

2328

ORF Size (bp)

2328 bp

RefSeq ID

NM_001178129

RefSeq Synonyms

NM_012431, NM_001178129, BC152458, BC144338, BC140706,

Species

human

UniGene ID

Hs.528721

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.