human RTN4 Over-expression AAV

Name 
AAV-h-RTN4
Cat No 
AAV-222092
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human RTN4.

AAV-222092
AAV-h-RTN4

Ready-to-use AAV expressing Human RTN4 (reticulon 4). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
ASY; Nbla00271; Nbla10545; NI220/250; NOGO; NOGO-A; Nogo-B; Nogo-C; NOGOC; NSP; NSP-CL; RTN-X; RTN4-A; RTN4-B1; RTN4-B2; RTN4-C
Description (Vector)
RTN4 belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. The product of this gene is a potent neurite outgrowth inhibitor which may also help block the regeneration of the central nervous system in higher vertebrates. Alternatively spliced transcript variants derived both from differential splicing and differential promoter usage and encoding different isoforms have been identified.
Gene ID
57142
Gene Name (Vector)
reticulon 4
Gene Symbol
RTN4
HGNC ID
HGNC:14085
ORF Size (aa)
597
RefSeq ID
NM_007008
RefSeq Synonyms
NM_207521, NM_207520, NM_153828, NM_020532, NM_007008, NM_001321904, NM_001321863, NM_001321862, NM_001321861, NM_001321860, NM_001321859, BC152555, BC152425, BC150182, BC139928, BC016165,
Species
human
UniGene ID
Hs.704007

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.