human TNFRSF6B Over-expression AAV

Name 
AAV-h-TNFRSF6B
Cat No 
AAV-222079
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human TNFRSF6B.

AAV-222079
AAV-h-TNFRSF6B

Ready-to-use AAV expressing Human TNFRSF6B (TNF receptor superfamily member 6b). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
DCR3; DJ583P15.1.1; M68; M68E; TR6
Description (Vector)
TNFRSF6B belongs to the tumor necrosis factor receptor superfamily. The encoded protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death. It acts as a decoy receptor that competes with death receptors for ligand binding. Over-expression of this gene has been noted in gastrointestinal tract tumors. Read-through transcription into this gene from the neighboring upstream gene, which encodes regulator of telomere elongation helicase 1 (RTEL1), generates a non-coding transcript.
Gene ID
8771
Gene Name (Vector)
TNF receptor superfamily member 6b
Gene Symbol
TNFRSF6B
HGNC ID
HGNC:11921
ORF Size (aa)
903
RefSeq ID
NM_003823
RefSeq Synonyms
NM_003823, BC034349, BC017065,
Species
human
UniGene ID
Hs.434878

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.